2,8-Diazaspiro[4.5]decan-1-one, 8-[3-chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]-
CCT251545
CAS: 1661839-45-7
Molecular Formula: C23H24ClN5O
2,8-Diazaspiro[4.5]decan-1-one, 8-[3-chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]- - Names and Identifiers
2,8-Diazaspiro[4.5]decan-1-one, 8-[3-chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]- - Physico-chemical Properties
| Molecular Formula | C23H24ClN5O |
| Molar Mass | 421.92 |
| Density | 1.37±0.1 g/cm3(Predicted) |
| Boling Point | 709.7±60.0 °C(Predicted) |
| Solubility | DMSO: ≥ 50 mg/mL |
| pKa | 15.81±0.20(Predicted) |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
2,8-Diazaspiro[4.5]decan-1-one, 8-[3-chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]- - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.37 ml | 11.851 ml | 23.701 ml |
| 5 mM | 0.474 ml | 2.37 ml | 4.74 ml |
| 10 mM | 0.237 ml | 1.185 ml | 2.37 ml |
| 5 mM | 0.047 ml | 0.237 ml | 0.474 ml |
Last Update：2024-01-02 23:10:35
2,8-Diazaspiro[4.5]decan-1-one, 8-[3-chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]- - Reference Information
| biological activity | CCT251545 is a potent, the IC50 value in 7dF3 cells was 5 nM. CCT251545 can also be used as a selective chemical probe to investigate the role of CDK8 and CDK19 in human diseases. |
| Target | Value |
| CDK8 () | |
| CDK19 () | |
| Wnt (in 7dF3 cells) | 5 nM |
Last Update：2024-04-09 20:52:54
![2,8-Diazaspiro[4.5]decan-1-one, 8-[3-chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]-](http://res.chembk.com/assets/str/2d/1/16/1661839-45-7.png)
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Spot supply
Product Name: CCT251545 Visit Supplier Webpage Request for quotationCAS: 1661839-45-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: CCT251545 Visit Supplier Webpage Request for quotationCAS: 1661839-45-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: CCT251545 Visit Supplier Webpage Request for quotationCAS: 1661839-45-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: CCT251545 Visit Supplier Webpage Request for quotationCAS: 1661839-45-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
2,8-Diazaspiro[4.5]decan-1-one, 8-[3-chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]-
2,5-呋喃二羧酰胺
2(1H)-Pyrimidinone, 4-amino-1-[6-(hydroxymethyl)-1,4-dioxan-2-yl]-, (2R-cis)- (9CI)
(3aR,4S,5R,6aS)-4-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]hexahydro-5-[(tetrahydro-2H-pyran-2-yl)oxy]-2H-cyclopenta[b]furan-2-one
2-苄基苯并呋喃-5-甲醛
(S)-对甲苯磺酸缩水甘油酯
MCL-1抑制剂(A-1210477)
2(1H)-Quinolinone, 3-[2-(3,5-dichlorophenyl)diazenyl]-4-hydroxy-1-phenyl-
methyl 3-hydroxybicyclo[1.1.1]pentane-1-carboxylate
2,5-呋喃二羧酰胺
2(1H)-Pyrimidinone, 4-amino-1-[6-(hydroxymethyl)-1,4-dioxan-2-yl]-, (2R-cis)- (9CI)
(3aR,4S,5R,6aS)-4-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]hexahydro-5-[(tetrahydro-2H-pyran-2-yl)oxy]-2H-cyclopenta[b]furan-2-one
2-苄基苯并呋喃-5-甲醛
(S)-对甲苯磺酸缩水甘油酯
MCL-1抑制剂(A-1210477)
2(1H)-Quinolinone, 3-[2-(3,5-dichlorophenyl)diazenyl]-4-hydroxy-1-phenyl-
methyl 3-hydroxybicyclo[1.1.1]pentane-1-carboxylate